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RETINAL DEGENERATION

Illuminating Molecular Complexities of the Retina

*Friday, April 7th 2006*

13:15 Eberhart Zrenner/Tübingen: Opening Remarks

13:25 Christina Fasser/Retina International: "From the Patient’s View"

13:40 Frank G. Holz/Bonn: "Visualization and Diagnosis of Retinal Disease - Advances in Imaging Technology"

14:00-15:30 *Session 1: The Connecting Cilium and Neurodegeneration*
Chairman: Frank G. Holz

# Uwe Wolfrum/Mainz: "Photoreceptor Cilium and Retinal Degeneration"

# Ronald Roepman/Nijmegen: "Getting a GRIP on RPGR - Dissection of the Protein Complex unveils its Importance for Retina Function"

# Christine Petit/Paris: "Hereditary Deafness: From Genes to Pathophysiology"

15:30-16:00 Coffee break and scientific chitchat

16:00-17:30 *Session 2: Cone-rod-interaction*
Chairman: Bernhard H. F. Weber

# Susanne Kohl/Tübingen: "Genetic Complexity of Cone and Cone-Rod Dystrophies"

# Thierry Leveillard/Paris: "Rod-derived Cone Viability Factor"

# Mathias Seeliger/Tübingen: "Functional Rod Pathways in Mice dissected with Electroretinography"

18:00 Joint Ceremonial Dinner

19:00-Open End *Postersession*

*Saturday, April 8th 2006*

08:30-10:30 *Session 3: Signalling Processes in the Retina*
Chairman: Olaf Strauß

# Ulrike Janssen-Bienhold/Oldenburg: "Diversity of the Connexins in Retinal Network Signalling"

# Katja Rillich/Leipzig: "Neuro-Glial Crosstalk in the Retina"

# Silke Haverkamp/Frankfurt: "Bipolar Cells of the Mouse Retina: Types and Plasticity"

# Katharina Wycisk/Zürich: "Structural and Functional Abnormalities of Retinal Ribbon Synapses due to Cacna2d4 Mutation"

# Christina Zeitz/Zürich: "Night Blindness-associated Mutations in the Metabotropic Glutamate Receptor 6 show a Distinctive Scotopic 15-Hz Flicker ERG and abolish Protein Trafficking"

10:30 Coffee break and scientific chitchat

11:00-13:00 *Session 4: The Biology of Neovascularization*
Chairman: Klaus Rüther

# Ernst Tamm/Regensburg: "Dissecting the Function of the Norrie Protein"

# Hans-Peter Hammes/Mannheim-Heidelberg: "Neovascularization of Retinal Vessels"

# Olaf Strauß/Hamburg: "The Role of the RPE Cells in Neovascularization of Choroidal Vessels"

# Andreas Bringmann/Leipzig: "Osmotic Swelling of Glial Cells in the Diabetic Rat Retina: Implications for the Development of Retinal Edema"

13:00 Lunch

14:15-15:45 *Session 5: Novel Aspects of AMD Etiology*
Chairman: Gareth McKay

# Claudia Keilhauer/Würzburg: "AMD Phenotypes and Aspects of Recruitment of Cases/Controls for Association Studies"

# Lars Fritsche/Regensburg: "Susceptibility Factors in AMD"

# Peter Zipfel/Jena: "The Role of the Complement System in AMD"

# Akshay Anand/Chandigarh: "The Animal Models of AMD – a Critical Appraisal"

15:45 Farewell Coffee

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