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April 3rd/4th, 2020

15th PRO RETINA Research Colloquium on Retinal Degeneration

Update on innovative apporaches - an interdisciplinary dialogue

Friday, April 03, 2020


13:00 – 13:05 Welcome remarks
Franz Badura (Amberg, Germany)


13:05 – 14:30 SESSION 1
Selected poster presentations
Eight abstracts to be selected


14:30 – 15:00 Keynote lecture
Krzysztof Palczewski (Irvine, USA)
Systems pharmacology for acquired and
inherited retinal diseases


15:00 – 15:45 Coffee break

15:45 – 17:25 SESSION 2
Precision medicine – innovative
approaches


15:45 – 16:10 Rob W. J. Collin (Nijmegen, The Netherlands)
Splicing modulation therapy for inherited
retinal disease using antisense oligonucleotides


16:10 – 16:35 Mathew Pletcher (Basel, Switzerland)
Precision medicine for rare diseases –
challenges and opportunities.
An industry perspective


16:35 – 17:00 Yasmina Cehajic-Kapetanovic (Oxford, UK)
Gene therapy for RPGR-related RP – strategy
and first results from a clinical trial


17:00 – 17:25 Hendrik Scholl (Basel, Switzerland)
Pharmacotherapy for Stargardt disease


17:30 Dinner


19:00 – 20:00 EVENING LECTURE
Peter Campochiaro (Baltimore, USA)
Oxidative damage and cone dysfunction
and degeneration in retinitis pigmentosa


20:00 – open Swingin’ poster session

 

Saturday, April 04, 2020

 
09:00 – 10:40 SESSION 3
Innovative model systems and
technologies


09:00 – 09:25 Patricia Berber (Regensburg, Germany)
An introduction to retinal organoids


09:25 – 09:50 Mike Karl (Dresden, Germany)
Human retina organoid model for
macular degeneration


09:50 – 10:15 Dwight Stambolian (Pennsylvania, USA)
Using single cell RNA-seq to understand
dysfunction in age-related macular
degeneration


10:15 – 10:40 Elvir Becirovic (München, Germany)
CRISPR/Cas9-mediated gene activation:
A versatile approach for treatment of
inherited retinal diseases


10:40 – 11:15 Coffee break


11:15 – 12:55 SESSION 4
Immunity and the retina


11:15 – 11:40 Mike Sapieha (Montreal, Canada)
Innate immunity in retinal vascular
remodeling


11:40 – 12:05 Martin Zinkernagel (Bern, Switzerland)
Non-invasive imaging of immune cells
in the retina


12:05 – 12:30 Anne Wolf (Köln, Germany)
TSPO links reactive oxygen species with
neurotoxic microglia


12:30 – 12:55 Torben Lykke Sørensen (Kopenhagen,
Denmark)
Systemic immune activation in AMD


12:55 – 13:00 Concluding remarks


13:00 Lunch and end of meeting

 

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